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Review2020

A multidisciplinary approach to soft-tissue sarcoma of the extremities.

Nakayama R, Mori T, Okita Y, Shiraishi Y, Endo M · Expert review of anticancer therapy

Sarcoma subtypes

Abstract

INTRODUCTION: Soft-tissue sarcoma (STS) denotes a group of rare and highly heterogeneous malignant tumors of mesenchymal origin. Accurate histological diagnosis is critical for selecting appropriate treatment. Complete tumor resection is the primary treatment for STS, and the efficacies of radiotherapy and chemotherapy have been tested in the adjuvant setting to improve oncological outcomes. Because most STS lesions arise in the extremities, preserving limb function and managing limb impairment after radical local treatment represent significant challenges.

AREAS COVERED: This article reviews the current front-line treatments for patients with extremity STS and discusses the multidisciplinary team-based efforts needed to improve oncological outcomes and survivorship.

EXPERT OPINION: Given the rarity, variety, and complexity of STS, a multidisciplinary approach involving experts in various disciplines is vital for improving outcomes in patients ranging from diagnosis to survivorship. A major challenge is building a sustainable system in each region permitting all patients with extremity STS to be treated at high-volume centers with multidisciplinary teams dedicated to this rare and complex disease.

Shown exactly as published on PubMed. Your oncologist is the right person to judge whether these findings apply to your situation.

Publication type

Journal ArticleReview

Source: PubMed, PMID 32820961. Always confirm details with the original publication or your oncologist.