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Review2025

Rhabdomyosarcomas of Bone: An Update.

Shah A, Folpe AL · Surgical pathology clinics

Sarcoma subtypes

Abstract

This article discusses very rare rhabdomyosarcomas of bone, in particular, those harboring FET::TFCP2 (EWSR1 or FUS::TFCP2) or MEIS1::NCOA2 fusions. The diagnosis of these tumors may be challenging, owing to their rarity, and requires integrations of clinical, radiologic, morphologic, immunohistochemical, and molecular genetic data. The differential diagnosis of osseous rhabdomyosarcomas is also discussed.

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Publication type

Journal ArticleReview

Source: PubMed, PMID 40716918. Always confirm details with the original publication or your oncologist.