In Vivo Lung Perfusion for Pulmonary Metastases of Sarcoma

Shown exactly as written on ClinicalTrials.gov. Your oncologist is the right person to judge whether it fits your situation.

Inclusion Criteria:

* Diagnosis of Soft Tissue or Osteogenic Sarcoma
* Presence of bilateral pulmonary metastases
* 3 or more lung lesions in total
* Age less than 65 years
* ECOG 0-2
* Absence of extra-pulmonary disease
* Contralateral disease amenable to surgery or radiation
* All lung lesions in the lung to be treated with IVLP can be resected with wedge or segmental resections (non-IVLP treated lung will be treated with radiation or surgery 4-12 weeks prior to IVLP)

Exclusion Criteria:

* Patient has previously received more than 450 mg of doxorubicin
* Left Ventricular Ejection Fraction \<50%
* History of significant pulmonary disease or pneumonitis
* Pregnant or lactating females
* Age 65 years or older, or less than 18 years
* Inability to understand the informed consent process
* Hypersenstivity to doxorubicin
* Current participation in another therapeutic clinical trial
* Previous lung metastatectomy