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INPWT on Wound Complications & Clinical Outcomes After Lower Extremity Sarcoma Surgery Preop Radiation Therapy Patients

Sponsor: Dr. J. Werier · NCT03175718 on ClinicalTrials.gov ↗

Conditions studied

Soft-tissue SarcomaWound Complication

What it tests

  • Incisional Negative Pressure Wound Therapy (INPWT)other
  • Wound Dressingother

Where it's running2 sites

2 international sites
See the official eligibility language

Shown exactly as written on ClinicalTrials.gov. Your oncologist is the right person to judge whether it fits your situation.

Inclusion Criteria:

* Patients 18 years of age and older and are able to provide written consent.
* Patients with lower extremity soft tissue sarcoma confirmed by tissue pathology.Each patient must have local cross sectional imaging (CT or MRI) and a staging CT chest.
* Patients eligible for treatment with preoperative radiation therapy followed by limb salvage surgery.
* Patients for which a primary closure must be attained at the time of surgery.
* Patient must be available for postoperative follow-up at the treating center.

Exclusion Criteria:

* Patients who are less than 18 years of age.
* Patients with a benign disease or with prior radiation to the anatomic region in the remote past (not associated with current treatment radiation plans).
* Patients who underwent surgical amputation
* Patients in which primary closure was not achieved (including free flaps and split thickness skin grafts).
* Patients with a life expectancy less than 120 days.
* Patients who have an allergy or sensitivity to adhesive dressings.

Updated 2026-03-02 on ClinicalTrials.gov. Always confirm current details with the study team or your oncologist.