Pemetrexed, Cisplatin With Soft Tissue Sarcoma

Shown exactly as written on ClinicalTrials.gov. Your oncologist is the right person to judge whether it fits your situation.

Inclusion Criteria:

* histologically confirmed, advanced/metastatic STS
* Is ≥ 19 years of age
* Eastern Cooperative Oncology Group performance status of 0 or 1
* measurable disease per Response Evaluation Criteria in Solid Tumors Version 1.1
* laboratory values indicating adequate organ function
* a documented postmenopausal woman, or is a premenopausal woman with negative urine or serum pregnancy test
* life expectancy ≥ 12 weeks

Exclusion Criteria:

* previously received more than 2 regimens of cytotoxic chemotherapy
* received chemotherapy, surgery to major organ, or radiotherapy within the last 2 weeks
* ongoing toxicity (≥ CTCAE grade 2) from previous anticancer therapy
* central nervous system (CNS) metastases requiring active treatment
* diagnosis of second malignancy or has a history of active malignancy within the past 3 years
* other medical conditions where the study treatment is intolerable
* history of active infection
* hypersensitivity to pemetrexed or any of its excipients
* Co-administration with yellow fever vaccine
* pregnancy