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Recruiting nowUp to 24 Years

Genomic Profiles Analysis in Children, Adolescents and Young Adult With Sarcomas

Sponsor: Azienda Ospedaliera Ospedale Infantile Regina Margherita Sant'Anna · NCT04621201 on ClinicalTrials.gov ↗

Conditions studied

Diagnosed or Relapsed/Refractory Sarcomas

What it tests

  • observation and biopsyother

Where it's running10 sites

10 international sites
  • AOU Città della Salute e della Scienza di Torino - Presidio Infantile Regina Margherita

    Torino, Turin, Italy 10126

    Recruiting now
  • Istituto Ortopedico Rizzoli

    Bologna, Italy

    Recruiting now
    • Emanuela Palmerini(contact)
  • Policlinico S.Orsola-Malpighi

    Bologna, Italy

    Recruiting now
    • Arcangelo Prete(contact)
  • Azienda ospedaliero-universitaria Meyer

    Florence, Italy

    Recruiting now
    • Angela Tamburrini(contact)
  • Istituto Giannina Gaslini

    Genova, Italy

    Recruiting now
    • Alberto Garaventa(contact)
  • Istituto Nazionale Tumori

    Milan, Italy

    Recruiting now
    • Roberto Luksch(contact)
  • Presidio Ospedaliero Gaetano Pini | ASST Pini-CTO

    Milan, Italy

    Suspended
  • Fondazione I.R.C.C.S. Policlinico San Matteo

    Pavia, Italy

    Recruiting now
    • Marco Zecca(contact)
  • Istituti fisioterapici Ospitalieri - Istituto Tumori Regina Elena e Istituto Dermatologico San Gallicano

    Roma, Italy

    Active, not recruiting
  • IRCCS materno infantile Burlo Garofolo

    Trieste, Italy

    Recruiting now
    • Marco Rabusin(contact)
See the official eligibility language

Shown exactly as written on ClinicalTrials.gov. Your oncologist is the right person to judge whether it fits your situation.

Inclusion Criteria:

1. Patients with histologically confirmed Osteosarcoma, Ewing Sarcoma or Synovial Sarcoma at first diagnosis.
2. Patients with confirmed relapsed/refractory Osteosarcoma, Ewing Sarcoma or Synovial Sarcoma
3. Written informed consent signed by the patient, or parents or legal representative to perform molecular analysis of the tumor sample.
4. Patients aged ≤24 years
5. Pathological review of tumor samples.
6. Availability of fresh tumor sample from newly diagnosed or relapsed/refractory cancer and 10 ml of EDTA peripheral blood sample. Centralization of paraffin-embedded tumor sample might be optional.

Exclusion Criteria:

* 1\. Known history of active HIV, HCV, or HBV infection 2. Presence of a condition or abnormality that in the opinion of the Investigator would compromise the safety of the patient undergoing surgery biopsy or the quality of the data.

Updated 2023-03-29 on ClinicalTrials.gov. Always confirm current details with the study team or your oncologist.