Fluorescent Intra-operative Tumor Margin Examination

Shown exactly as written on ClinicalTrials.gov. Your oncologist is the right person to judge whether it fits your situation.

Inclusion Criteria:

* Patients above the age of 18 with a primary musculoskeletal tumor that has been indicated for surgical excision by a fellowship trained orthopaedic oncologist.
* Surgical consent was obtained prior to research consent.
* Patients with a biopsy-confirmed primary soft tissue or bone tumor that has not been previously excised and has a known risk of local or remote recurrence.

Exclusion Criteria:

* Patients below the age of 18
* Pregnancy, breast feeding
* Patients with a history of anaphylactic reaction to contrast media or fluorescein allergy
* Prior surgery local to the mass being excised
* Non- or minimally-recurrent masses (i.e. osteochondroma)
* Dialysis, renal failure, uremia