Recruiting now—Up to 40 Years

Observational Study in Localized Osteosarcoma

Sponsor: Italian Sarcoma Group · NCT04890067 on ClinicalTrials.gov ↗

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Conditions studied

Localized Osteosarcoma

What it tests

Treatment of Osteosarcoma according the AIEOP/ISG OS 2021 recommendations (includes drugs, surgery, radiotherapy or any other received treatments)other

Where it's running16 sites

16 international sites

Centro di Riferimento Oncologico - Unit of Medical Oncology
Aviano, Pordenone, Italy 33081
Recruiting now
- Maurizio Mascarin, MD(contact)+390434659 [email protected]
- Maurizio Mascarin, MD(principal investigator)
Sandra Aliberti
Candiolo, Torino, Italy 10060
Recruiting now
- Sandra Aliberti, MD(contact)0039-011-993 [email protected]
- Giovanni Grignani, MD(principal investigator)
IRCCS materno infantile Burlo Garofolo
Trieste, T, Italy 34137
Recruiting now
- Marco Rabusin, MD(contact)040.3785 [email protected]
- Marco Rabusin, MD(principal investigator)
Azienda Ospedaliero Universitaria Consorziale Policlinico - Bari
Bari, Italy 70124
Recruiting now
- Francesco De Leonardis, MD(contact)00390805592 [email protected]
- Francesco De Leonardis, MD(principal investigator)
IRCCS Istituto ortopedico Rizzoli
Bologna, Italy 40136
Recruiting now
- Toni Ibrahim, MD(contact)
- Michela Pierini, PhD(contact)+390516366 [email protected]
- Toni Ibrahim, MD(principal investigator)
A.O. Universitaria Policlinico S. Orsola Malpighi di Bologna
Bologna, Italy 40138
Recruiting now
- Arcangelo Prete, MD(contact)+390516363 [email protected]
- Arcangelo Prete, MD(principal investigator)
AUO Policnico G. Rodolico San Marco
Catania, Italy 95123
Recruiting now
- Andrea Di Cataldo, MD(contact)
- (contact)[email protected]
A.O. Universitaria Meyer
Florence, Italy 50139
Recruiting now
- Angela Tamburini, MD(contact)+3905556 [email protected]
- Angela Tamburini, MD(principal investigator)
Istituto Giannina Gaslini
Genova, Italy
Recruiting now
- Carla Manzitti, MD(contact)
- (contact)"manzitti carla" <[email protected]>
- Carla Manzitti, MD(principal investigator)
Fondazione IRCCS INT Milano SC Pediatria Oncologica
Milan, Italy
Recruiting now
- Cristina Meazza, MD(contact)+390223903
- (contact)[email protected]
- Cristina Meazza, MD(principal investigator)
FONDAZIONE IRCCS Istituto Nazionale dei Tumori
Milan, Italy
Recruiting now
- Rossella Bertulli, MD(contact)
- (contact)[email protected]
- Rossella Bertulli, MD(principal investigator)
Azienda Ospedaliera di Padova UOC Oncoematologia Pediatrica
Padova, Italy
Recruiting now
- Gianni Bisogno, MD(contact)
- (contact)[email protected]
- Gianni Bisogno, MD(principal investigator)
ARNAS P. O. "Civico e Benfratelli"
Palermo, Italy 90127
Recruiting now
- Paolo D'Angelo, MD(contact)039 091666 [email protected]
Azienda Ospedaliero-Universitaria Pisana
Pisa, Italy 56126
Recruiting now
- Luca Coccoli, MD(contact)0039050992 [email protected]
- Luca Coccoli, MD(principal investigator)
Istituti Fisioterapici Ospitalieri di Roma
Roma, Italy
Recruiting now
- Virginia Ferraresi, MD(contact)
- (contact)[email protected]
- Virginia Ferraresi, MD(principal investigator)
Ospedale Pediatrico Bambin Gesu'
Roma, Italy
Opening soon
- Giuseppe Maria Milano, MD(contact)06 68591 [email protected]
- Giuseppe Maria Milano, MD(principal investigator)

See the official eligibility language

Shown exactly as written on ClinicalTrials.gov. Your oncologist is the right person to judge whether it fits your situation.

Inclusion Criteria:

* Diagnosis of high grade OS of the extremities
* Age at diagnosis ≤ 40 years at the time of diagnosis
* Localized disease (skip metastases are allowed)
* Adequate organ function according the AIEOP/ISG OS 2021 recommendation
* Patients or parents oe guardians of minors who have given their written informed consent to participate in the study

Exclusion Criteria:

* Presence of metastases
* Diagnosis of periosteal OS, of parosteal OS or secondary OS
* Any medical condition which can not allowed the use of the treatments recommended by AIEOP/ISG OS 2021

Updated 2026-03-27 on ClinicalTrials.gov. Always confirm current details with the study team or your oncologist.