Neoadjuvant Irradiation of Extremity Soft Tissue Sarcoma With Ions

Shown exactly as written on ClinicalTrials.gov. Your oncologist is the right person to judge whether it fits your situation.

Inclusion Criteria:

* Histologically confirmed soft-tissue sarcoma of the extremities with an indication for perioperative radiation treatment
* Resectable or marginally resectable
* Karnofsky index of ≥ 70%
* Age ≥ 18 years
* Carried out patient education and written consent
* Patient is capable to give informed consent

Exclusion Criteria:

* Stage IV (distant metastases)
* Lymph node metastasis
* Metal implants that influence treatment planning with ions
* Previous radiotherapy in the treatment area
* Desmoid tumors
* Simultaneous participation in another clinical trial that could influence the results of the study.
* Active medical implants for which no ion beam irradiation permit exists at the time of treatment (e.g., cardiac pacemaker, defibrillator)