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Recruiting nowAges 16 Years and up

Ex VIvo DEtermiNed Cancer Therapy

Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust · NCT05231655 on ClinicalTrials.gov ↗

Conditions studied

Bladder CancerKidney CancerMelanomaSarcomaGlioblastomaHead and Neck Cancer

What it tests

  • Functional drug screendiagnostic_test

Where it's running1 site

1 international site
  • Sheffield Teaching Hospitals NHS Foundation Trust

    Sheffield, South Yorkshire, United Kingdom S10 2JF

    Recruiting now
See the official eligibility language

Shown exactly as written on ClinicalTrials.gov. Your oncologist is the right person to judge whether it fits your situation.

Inclusion Criteria:

\>16 years of age with a diagnosis of known or suspected solid cancer who will undergo surgery, biopsy, aspirate, or TURBT

Willing to donate a section fresh tumour tissue from surgery, a TURBT, fluid aspirate, or biopsy surplus to diagnostic use

Willing to donate a 9ml blood sample

Able to give written informed consent

Previously treated patients are eligible if:

* Present with a recurrence of a previously treated tumour. This may be a local or metastatic recurrence
* Have undergone treatment for their cancer, but fail to respond to this and progress
* Have received neoadjuvant therapy for their tumour
* Have undergone chemotherapy, targeted therapy, immunotherapy, hormone therapy and or radiotherapy for a previous tumour

Exclusion Criteria:

Patients with a known diagnosis of a blood borne virus (Hepatitis B, Hepatitis C, HIV). (The laboratories where experiments will be conducted do not have the safety facilities to use material containing these pathogens)

Patients with a current positive COVID-19 infection

Updated 2025-02-24 on ClinicalTrials.gov. Always confirm current details with the study team or your oncologist.