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Pre-operative Hypofractionated Proton Therapy

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · NCT05917301 on ClinicalTrials.gov ↗

Conditions studied

Soft Tissue Sarcoma

What it tests

  • hypofractionationradiation

Where it's running1 site

See the official eligibility language

Shown exactly as written on ClinicalTrials.gov. Your oncologist is the right person to judge whether it fits your situation.

Inclusion Criteria:

* Adult patients (≥18 years of age)
* Patients with primary or locally recurrent extremity or truncal soft tissue sarcoma
* WHO/ECOG status ≤2

Exclusion Criteria:

* History of prior local radiation therapy
* Inability to tolerate treatment position for duration of simulation or treatment
* Tumor originating in retroperitoneal location
* Patients planned for systemic therapy including chemotherapy, targeted agents, and immunotherapy
* Co-existing malignancy or treated malignancy in the last 2 years expected to limit life expectancy; does not include completely resected cutaneous basal cell carcinoma, squamous cell carcinoma, in situ breast or cervical malignancies, or other pathologies at the discretion of the investigators.
* Confirmed pregnancy.

Updated 2026-04-17 on ClinicalTrials.gov. Always confirm current details with the study team or your oncologist.