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Study Comparing Negative Pressure Dressing vs Conventional in Patients With Resected STS After Radiotherapy

Sponsor: Centre Leon Berard · NCT05944913 on ClinicalTrials.gov ↗

Conditions studied

Soft Tissue Sarcoma

What it tests

  • Prevenadevice

Where it's running15 sites

15 international sites
See the official eligibility language

Shown exactly as written on ClinicalTrials.gov. Your oncologist is the right person to judge whether it fits your situation.

Inclusion Criteria:

* Age ≥ 18 years at the day of consenting to the study
* Patients with primary STS of the limb or trunk treated with preoperative external radiation therapy (decided in multidisciplinary board)
* Intent to cure resection required for STS planned between 3 to 8 weeks after the end of RT
* Planned primary wound closure, including local or distant jambeau
* Ability to understand and willingness for follow-up visits
* Covered by a medical insurance
* Signed and dated informed consent document indicating that the patient has been informed of all aspects of the trial prior to enrolment.

Exclusion Criteria:

* Known hypersensibility to silver
* Patients with a diagnosis of Ewing's sarcoma, chondrosarcoma, osteosarcoma, or desmoid tumor. Nota bene: Only patients with bone tumors are affected; patients with soft tissue tumors can be included in the study.
* Patient in relapse setting;
* Patient requiring a surgical revision after R1 or R2 resection;
* Planned blade drainage;
* Planned no wound-closure and skin graft after resection
* Patient requiring authorship or curators or patient deprived of liberty.

Updated 2025-08-08 on ClinicalTrials.gov. Always confirm current details with the study team or your oncologist.