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Upfront Surgical Resection for Osteosarcoma

Sponsor: Montefiore Medical Center · NCT06384404 on ClinicalTrials.gov ↗

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Conditions studied

Osteosarcoma

What it tests

  • Questionnaireother

Where it's running1 site

  • Montefiore Medical Center

    The Bronx, New York 10467

    Recruiting now
See the official eligibility language

Shown exactly as written on ClinicalTrials.gov. Your oncologist is the right person to judge whether it fits your situation.

Inclusion Criteria:

* Patients must have newly diagnosed, previously untreated, localized, high-grade osteosarcoma of an extremity (verified by histopathology) with plans to undergo upfront surgical resection of the tumor followed by systemic chemotherapy.
* Patients must have a performance status corresponding to Eastern Cooperative Oncology Group (ECOG) scores of 0, 1, or 2 (Karnofsky will be used for patients \>16 years of age and Lansky score for patients \<= 16 years of age)

Exclusion Criteria:

* Patients with metastatic disease at diagnosis
* Initiation of systemic therapy prior to enrollment
* Prior history of cancer
* Prior radiation therapy
* Active life-threatening infection
* Pregnancy (negative pregnancy test result must be obtained for female patients of childbearing potential)

Updated 2026-03-16 on ClinicalTrials.gov. Always confirm current details with the study team or your oncologist.