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Opening soonPhase 3Ages 18 Years and up

High Versus Lower Intensity Surveillance Following Resection of Retroperitoneal Sarcoma

Sponsor: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano · NCT06480396 on ClinicalTrials.gov ↗

Conditions studied

Sarcoma,Soft TissueSarcoma Retroperitoneal

What it tests

  • High-intensity radiological surveillancediagnostic_test
  • Lower-intensity radiological surveillancediagnostic_test

Where it's running2 sites

2 international sites
See the official eligibility language

Shown exactly as written on ClinicalTrials.gov. Your oncologist is the right person to judge whether it fits your situation.

Inclusion Criteria:

* Adult patients (greater than 18 years)
* Primary resection
* Histologically confirmed retroperitoneal, abdominal or pelvic soft tissue sarcoma
* R0/R1 resection
* Eligible whether or not the participant undergoes neoadjuvant treatment

Exclusion Criteria:

* Metastatic disease at time of randomisation
* Recurrent, metastatic or residual disease identified on baseline CT imaging (3-4 months post primary resection)
* Reoperation for recurrent soft tissue sarcoma
* Re-resection following previous inadequate surgery
* R2 resection
* Patients receiving adjuvant therapy that will delay, interrupt or render radiological surveillance unpredictable
* Uterine sarcomas, gastrointestinal stromal tumour (GIST), fibromatosis, epithelial tumours, multifocal disease, sarcomas of bony origin
* Patient declined to consent to data sharing with RESAR (unless in a centre contributing via pre-planned IPDMA)

Updated 2024-10-16 on ClinicalTrials.gov. Always confirm current details with the study team or your oncologist.