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Opening soonPhase 2Ages 60 Years to 90 Years

AZA Combined with R-GemOx for Elderly DLBCL Patients

Sponsor: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University · NCT06778902 on ClinicalTrials.gov ↗

Conditions studied

DLBCL - Diffuse Large B Cell Lymphoma

What it tests

  • azacytidinedrug
  • R-GemOxdrug

Where it's running1 site

1 international site
See the official eligibility language

Shown exactly as written on ClinicalTrials.gov. Your oncologist is the right person to judge whether it fits your situation.

Key Inclusion Criteria:

1. Subjects fully understand and voluntarily participate in this study and sign informed consent.
2. Aged ≥60 years, both male and female.
3. Pathologically confirmed DLBCL
4. There must be at least one measurable or evaluable lesion that meets the evaluation criteria for Lugano 2014 lymphoma.
5. No previous chemotherapy or radiotherapy for DLBCL has been received.
6. Expected survival ≥3 months.

Key Exclusion Criteria:

1. DLBCL combined with other types of lymphoma. Transformed DLBCL.
2. DLBCL with central nervous system invasion.
3. The patients have contraindications to any drug in the combined treatment.
4. Patients with the infection of human immunodeficiency virus (HIV) and/or acquired immunodeficiency syndrome.
5. Mentally ill persons or persons unable to obtain informed consent.
6. The investigators think that the patient is not suitable for the study.

Updated 2025-01-16 on ClinicalTrials.gov. Always confirm current details with the study team or your oncologist.