Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's Lymphoma

Shown exactly as written on ClinicalTrials.gov. Your oncologist is the right person to judge whether it fits your situation.

Inclusion Criteria:

* Participants diagnosed with solid tumors, including Rhabdomyosarcoma, Osteosarcoma, Ewing sarcoma, other sarcomas and carcinomas or also Hodgkin's lymphoma.
* Participants who receive proton radiation therapy at St. Jude Children's Research Hospital.
* Research participant or legal guardian/representative gives written informed consent.

Exclusion Criteria:

* Participants who are not diagnosed with solid tumors or Hodgkin's lymphoma.
* Participants who are diagnosed with Wilm's tumor or neuroblastoma
* Participants who do not undergo proton therapy.
* Participants who are prescribed equal or less than 5 fractions of proton therapy.
* Participants with severe comorbid conditions that may impact imaging feasibility.
* Inability to obtain written consent from research participant or legal guardian/representative.
* Females of child-bearing potential cannot be pregnant or breast-feeding. Female participants \>10 years of age or post-menarchal must have a negative serum or urine pregnancy test

All participants receiving proton therapy at St. Jude Children's Research Hospital will be screened for participation on this research protocol based on the Inclusion Criteria and the Exclusion Criteria. Qualified candidates will be selected during the consultation.