Effectiveness of 0.9% Normal Saline Soaking in Managing Acute Radiation Dermatitis

Shown exactly as written on ClinicalTrials.gov. Your oncologist is the right person to judge whether it fits your situation.

Inclusion Criteria:

* Age ≥ 18 years
* Eastern Cooperative Oncology Group (ECOG) performance status 0-1
* Patients receiving definitive radiotherapy for sarcomas or head and neck cancer (primary or postoperative treatment)
* Planned radiation dose between 60-70 Gy according to disease-specific protocols
* No prior history of malignancy other than sarcomas
* Ability and willingness to comply with study procedures (\>90% expected adherence)
* Signed informed consent

Exclusion Criteria:

* Patients receiving palliative radiotherapy
* Known pre-existing skin disorders affecting radiation area (e.g., systemic lupus erythematosus, scleroderma)
* ECOG performance status ≥2
* Previous radiotherapy to the same treatment field
* Any condition that, in the investigator's judgment, may interfere with participation or wound healing assessment