A Novel Two-Tooth Clip for ESD and EFTR of GIST

Shown exactly as written on ClinicalTrials.gov. Your oncologist is the right person to judge whether it fits your situation.

Inclusion Criteria:

* Age ≥ 18 and ≤ 85 years.
* Patients diagnosed with gastric gastrointestinal lesions clinically indicated for ESD or EFTR.
* Lesion size between 2 cm and 5 cm in diameter.
* Willing and able to provide written informed consent.

Exclusion Criteria:

* Lesions with clear evidence of deep submucosal invasion or distant metastasis precluding curative endoscopic resection.
* Severe coagulation dysfunction (international normalized ratio \>2.0, platelet count \<50,000/µL) or ongoing use of dual antiplatelet therapy/anticoagulants that cannot be appropriately bridged or discontinued per guidelines.
* Severe organ failure (cardiac, renal, hepatic, or respiratory) rendering the patient unsuitable for prolonged sedation or general anesthesia.
* Pregnancy or lactation.
* Prior surgical or endoscopic intervention at the target lesion site that results in significant fibrosis.