Fluorescence-Guided Surgical Resection for Reducing Unexpected Positive Margins in Patients With Sarcoma, SarcoSIGHT Trial

Shown exactly as written on ClinicalTrials.gov. Your oncologist is the right person to judge whether it fits your situation.

Inclusion Criteria:

* Documented written informed consent of the participant
* Histologically confirmed diagnosis of intermediate to high grade sarcoma
* All ages
* Amenable to surgical resection as a part of curative intent for the patient
* Willingness to:

  * Respond to surveys during the trial
  * Permit medical record/ clinical laboratory result review

Exclusion Criteria:

* Due for surgery with palliative intent
* Recurrent tumors
* Intracranial, retroperitoneal, and visceral anatomical locations
* A woman of childbearing potential who is currently pregnant (as confirmed by urine pregnancy test)
* A woman who are currently breastfeeding
* Known allergies to ICG, iodine, iodine dyes or shellfish
* Unable to provide written and informed consent
* Patients with hyper-thyroidism or autonomic thyroid adenomas
* Premature infants/neonates with exchange transfusion indication due to hyperbilirubinemia